Product Name :
PRAK Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
MAP kinase-activated protein kinase 5 antibody MAPK-activated protein kinase 5 antibody MAPK5_HUMAN antibody MAPKAP kinase 5 antibody MAPKAPK-5 antibody MAPKAPK5 antibody Mitogen activated protein kinase activated protein kinase 5 antibody p38-regulated/activated protein kinase antibody PRAK antibody
Function :
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta.DSPE-MPEG2000 Formula The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human MAPKAPK5. AA range:148-197
Species reactivity:
Human, Mouse
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.(4-Methylpyridin-3-yl)boronic acid custom synthesis Aliquot store at -20℃ or -80℃.PMID:33676822 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
60 kDa
Positive control :
Brain,Cervix,Pancreas,Placenta,