Product Name :
PSPC1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Paraspeckle component 1 antibody Paraspeckle protein 1 antibody PSP1 antibody Pspc1 antibody PSPC1_HUMAN antibody
Function :
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from human protein . at AA range: 10-90
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2-Bromo-3,4-difluorobenzonitrile web Aliquot store at -20℃ or -80℃.(3-Hydroxy-5-methylphenyl)boronic acid Data Sheet Avoid repeated freeze / thaw cycles.PMID:33583768
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
57 kDa
Positive control :
Kidney,Placenta,Skin,