Product Name :
RBPMS Guinea Pig Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
RNA-binding protein with multiple splicing Heart and RRM expressed sequence
Function :
This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity.1956434-67-5 Price Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1.3-Aminobutan-2-ol Chemscene Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
Antibody Type:
Guinea Pig Polyclonal Antibody
Immunogen :
Synthetic peptide within human RBPMS 1-30 conjugated to Keyhole Limpet Haemocyanin.
Species reactivity:
Human, Mouse
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
AB_3069301
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33455008 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
1:1,000-1:5,000
Molecular weight :
21 kDa
Positive control :
Ubiquitously expressed, at various levels depending on the isoform and the tissue.