Product Name :
ST2 Mouse Monoclonal Antibody [PSH01-69]
Predicted band size :
63 kDa
Observed band size :
80 kDa
Synonyms:
DER-4 antibody DER4 antibody FIT 1 antibody Growth stimulation expressed antibody homolog of mouse growth stimulation-expressed antibody Il1rl1 antibody IL33R antibody ILRL1_HUMAN antibody Interleukin 1 receptor like 1 antibody interleukin 1 receptor related protein antibody 展开
Function :
Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function (Probable). Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within human ST2 aa 19-328 (Extracellular).1215071-17-2 manufacturer
Species reactivity:
Human
Verify application:
WB, IF-Cell, FC
Coupling :
unconjugated
Clone number:
PSH01-69
RRID:
AB_3071890
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Methyl 6-amino-2-methylnicotinate supplier Aliquot store at -20℃.PMID:33475051 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 63.4 kDa
Positive control :
HeLa transfected with FLAG-tagged ST2 cell lysate, HeLa overexpress with ST2.