Product Name :
UTF1 Mouse Monoclonal Antibody [E0-F4]
Predicted band size :
Observed band size :
Synonyms:
hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody
Function :
Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Synthetic peptide within Human UTF1 aa 51-100 / 341.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell
Coupling :
unconjugated
Clone number:
E0-F4
RRID:
AB_3073087
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing.1018446-95-1 Chemical name Aliquot store at -20℃ or -80℃.Buy236406-49-8 Avoid repeated freeze / thaw cycles.PMID:33741792
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG2b
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
36-50 kDa
Positive control :
D3