Product Name :
VPAC1 Recombinant Rabbit Monoclonal Antibody [PD00-96]
Predicted band size :
52 kDa
Observed band size :
55 kDa
Synonyms:
FLJ41949 antibody HVR 1 antibody HVR1 antibody PACAP R 2 antibody PACAP type II receptor antibody PACAP-R-2 antibody PACAP-R2 antibody Pituitary adenylate cyclase activating polypeptide receptor type II antibody Pituitary adenylate cyclase activating polypeptide type II receptor antibody Pituitary adenylate cyclase-activating polypeptide type II receptor antibody 展开
Function :
There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors are activated by the endogenous peptides VIP, PACAP-38, PACAP-27, peptide histidine isoleucineamide (PHI), peptide histidine methionineamide (PHM) and peptide histidine valine (PHV). Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human VIPR1 aa 400-457.
Species reactivity:
Human, Mouse, Rat, Monkey
Verify application:
IHC-P, WB
Coupling :
unconjugated
Clone number:
PD00-96
RRID:
AB_3072329
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.6-Bromo-8-iodoquinolin-2(1H)-one supplier Aliquot store at -20℃.BuyTriisopropoxy(methyl)titanium Avoid repeated freeze / thaw cycles.PMID:33477174
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 52 kDa
Positive control :
HeLa cell lysate, Jurkat cell lysate, Raji cell lysate, HT-29 cell lysate, Caco-2 cell lysate, MCF7 cell lysate, MDA-MB-231 cell lysate, PC-12 cell lysate, LNCaP cell lysate, human tonsil tissue, NIH/3T3 cell lysate, C2C12 cell lysate, COS-1 cell lysate, C6 cell lysate, L6 cell lysate, mouse liver tissue lysate, mouse lung tissue lysate, mouse small intestine tissue lysate, mouse colon tissue lysate, rat lung tissue lysate, rat liver tissue lysate, human liver tissue, mouse liver tissue, rat liver tissue, rat spleen tissue.