Product Name :
PKD1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Autosomal dominant polycystic kidney disease 1 protein antibody Autosomal dominant polycystic kidney disease protein 1 antibody nPKC-D1 antibody nPKC-mu antibody OTTHUMP00000208669 antibody OTTHUMP00000208670 antibody PBP antibody Pc-1 antibody PKD antibody Pkd1 antibody 展开
Function :
This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis.150529-93-4 site It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on c
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from human protein .Methyl 5-bromo-4-iodonicotinate Chemical name at AA range: 1370-1450
Species reactivity:
Human
Verify application:
IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33565025 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
473 kDa
Positive control :
Brain,Epithelium,