Product Name :
PK1IP Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
p21-activated protein kinase-interacting protein 1 PAK1IP1 antibody p21-activated protein kinase-interacting protein 1 PIP1 antibody p21-activated protein kinase-interacting protein 1 WDR84 antibody
Function :
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. Contains 5 WD repeats. subunit:Interacts with PAK1. tissue specificity:Expressed in brain, colon, heart, kidney, liver, lung, muscle, peripheral blood leukocytes, placenta, small intestine, spleen and thymus.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from part region of human protein
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2409005-96-3 Chemscene Aliquot store at -20℃ or -80℃.681004-50-2 supplier Avoid repeated freeze / thaw cycles.PMID:33533261
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
43 kDa
Positive control :
Epithelium,Prostate,