Product Name :
PSIP1 Mouse Monoclonal Antibody [B11-E4]
Predicted band size :
Observed band size :
Synonyms:
CLL associated antigen KW 7 antibody CLL-associated antigen KW-7 antibody Dense fine speckles 70 kDa protein antibody DFS 70 antibody DFS70 antibody LEDGF antibody Lens epithelium derived growth factor antibody Lens epithelium-derived growth factor antibody MGC74712 antibody p52 antibody 展开
Function :
PSIP1 (PC4 and SFRS1 interacting protein 1), also known as CLL-associated antigen KW-7, PSIP2, LEDGF (lens epithelium-derived growth factor), PAIP, DFS70 (dense fine speckles 70 kDa protein) or transcriptional coactivator p75/p52, is a 530 amino acid nuclear protein that associates with chromatin throughout the cell cycle. Functioning as a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase, PSIP1 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, PSIP1 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, PSIP1 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders.856412-22-1 site
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Purified recombinant fragment of human CAMK2G (AA: 322-481) expressed in E.3-Formyl-1H-indazole-5-carboxylic acid custom synthesis Coli.
Species reactivity:
Human, Monkey, Rat
Verify application:
WB, ICC, IHC-P
Coupling :
unconjugated
Clone number:
B11-E4
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.PMID:33632601
Storage buffer solution:
Purified antibody in PBS with 0.05% sodium azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
75 kDa
Positive control :
HepG2, Jurkat, K562, Cos7, PC-12, Hela, NIH/3T3, human lung cancer tissue, brain tissue, human breast cancer tissue, human ovarian cancer tissue.