Product Name :
Villin1 Recombinant Rabbit Monoclonal Antibody [JU34-75]

Predicted band size :
93 kDa

Observed band size :
93 kDa

Synonyms:
D2S1471 antibody OTTHUMP00000164145 antibody VIL antibody VIL1 antibody VILI_HUMAN antibody Villin 1 antibody Villin-1 antibody Villin1 antibody

Function :
Caldesmon, Filamin 1, Nebulin and Villin are differentially expressed and regulated Actin binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon have been identified and each has been shown to bind to Actin as well as to calmodulin and myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CDl is widely expressed in non-muscle tissues and cells. Filamin 1, which is ubiquitously expressed and exists as a homodimer, functions to crosslink Actin to filaments. Nebulin is a large filamentous protein specific to muscle tissue that may function as a ruler for filament length. Several isoforms of Nebulin are produced by alternative exon usage. Villin is Ca2+-regulated and is the major structural component of the brush border of absorptive cells.

Antibody Type:
Recombinant Rabbit monoclonal Antibody

Immunogen :
Synthetic peptide within Human Villin1 aa 176-225 / 827.

Species reactivity:
Human, Mouse, Rat

Verify application:
WB, IF-Cell, IHC-P, FC, mIHC

Coupling :
unconjugated

Clone number:
JU34-75

RRID:
AB_3070682

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing.Thiol-C2-PEG2-OH web Aliquot store at -20℃ or -80℃.Triazabicyclodecene web Avoid repeated freeze / thaw cycles.PMID:33455046

Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 93 kDa

Positive control :
Caco-2 cell lysate, COLO205 cell lysate, AGS cell lysate, Hela, HepG2, LOVO, human colon cancer tissue, human kidney tissue, mouse colon tissue.